COL4A2-ELK3 Fusion FISH Probe
The COL4A2-ELK3 Fusion FISH Probe is used to confirm a fusion of the COL4A2 and ELK3 genes. The fusion of the COL4A2 and ELK3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL4A2-ELK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-RERE | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-REOR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-REGO | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-REGR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-REAQ | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-ORRE | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-OROR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-ORGO | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GORE | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GOOR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GOGO | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GOGR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GRRE | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GROR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GRGO | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GRGR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-AQRE | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-AQOR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-AQGO | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-AQGR | 20 (40 μL) | 200 μL |
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| COL4A2-ELK3-20-AQAQ | 20 (40 μL) | 200 μL |
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COL4A2 Gene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type IV Alpha 2 Chain
Chromosome: CHR13: 110959630 -111165373
Locus: 13q34
ELK3 Gene Summary
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: ELK3, ETS Transcription Factor
Chromosome: CHR12: 96588206 -96661606
Locus: 12q23.1
Gene Diseases
The COL4A2 ELK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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