COL4A1-ZNF675 Fusion FISH Probe
The COL4A1-ZNF675 Fusion FISH Probe is used to confirm a fusion of the COL4A1 and ZNF675 genes. The fusion of the COL4A1 and ZNF675 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL4A1-ZNF675-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-RERE | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-REOR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-REGO | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-REGR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-REAQ | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-ORRE | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-OROR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-ORGO | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-ORAQ | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GORE | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GOOR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GOGO | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GOGR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GOAQ | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GRRE | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GROR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GRGO | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GRGR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-GRAQ | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-AQRE | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-AQOR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-AQGO | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-AQGR | 20 (40 μL) | 200 μL |
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| COL4A1-ZNF675-20-AQAQ | 20 (40 μL) | 200 μL |
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COL4A1 Gene Summary
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Collagen Type IV Alpha 1 Chain
Chromosome: CHR13: 110801309 -110959496
Locus: 13q34
ZNF675 Gene Summary
The Zinc Finger Protein 675 (ZNF675) gene is located on chr19 :23835707-23870017 at 19p12.
Gene Name: Zinc Finger Protein 675
Chromosome: CHR19: 23835707 -23870017
Locus: 19p12
Gene Diseases
The COL4A1 ZNF675 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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