COL3A1-STAT6 Fusion FISH Probe
The COL3A1-STAT6 Fusion FISH Probe is used to confirm a fusion of the COL3A1 and STAT6 genes. The fusion of the COL3A1 and STAT6 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL3A1-STAT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| COL3A1-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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COL3A1 Gene Summary
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Name: Collagen Type III Alpha 1 Chain
Chromosome: CHR2: 189839098 -189877472
Locus: 2q32.2
STAT6 Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Signal Transducer And Activator Of Transcription 6
Chromosome: CHR12: 57489186 -57505196
Locus: 12q13.3
Gene Diseases
The COL3A1 STAT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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