COL1A2-WNT2 Fusion FISH Probe
The COL1A2-WNT2 Fusion FISH Probe is used to confirm a fusion of the COL1A2 and WNT2 genes. The fusion of the COL1A2 and WNT2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL1A2-WNT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-RERE | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-REOR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-REGO | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-REGR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-REAQ | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-ORRE | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-OROR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-ORGO | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GORE | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GOOR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GOGO | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GOGR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GRRE | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GROR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GRGO | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GRGR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-AQRE | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-AQOR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-AQGO | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-AQGR | 20 (40 μL) | 200 μL |
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| COL1A2-WNT2-20-AQAQ | 20 (40 μL) | 200 μL |
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COL1A2 Gene Summary
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Name: Collagen Type I Alpha 2 Chain
Chromosome: CHR7: 94023872 -94060544
Locus: 7q21.3
WNT2 Gene Summary
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Wnt Family Member 2
Chromosome: CHR7: 116916685 -116963343
Locus: 7q31.2
Gene Diseases
The COL1A2 WNT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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