COG5-FOXP2 Fusion FISH Probe
The COG5-FOXP2 Fusion FISH Probe is used to confirm a fusion of the COG5 and FOXP2 genes. The fusion of the COG5 and FOXP2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COG5-FOXP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-RERE | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-REOR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-REGO | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-REGR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-REAQ | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-ORRE | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-OROR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-ORGO | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GORE | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GOOR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GOGO | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GOGR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GRRE | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GROR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GRGO | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GRGR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-AQRE | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-AQOR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-AQGO | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-AQGR | 20 (40 μL) | 200 μL |
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| COG5-FOXP2-20-AQAQ | 20 (40 μL) | 200 μL |
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COG5 Gene Summary
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
Gene Name: Component Of Oligomeric Golgi Complex 5
Chromosome: CHR7: 106842188 -107204959
Locus: 7q22.3
FOXP2 Gene Summary
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Name: Forkhead Box P2
Chromosome: CHR7: 113726364 -114333827
Locus: 7q31.1
Gene Diseases
The COG5 FOXP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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