CNTN2-PKP1 Fusion FISH Probe
The CNTN2-PKP1 Fusion FISH Probe is used to confirm a fusion of the CNTN2 and PKP1 genes. The fusion of the CNTN2 and PKP1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNTN2-PKP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-RERE | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-REOR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-REGO | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-REGR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-OROR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GORE | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GROR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CNTN2-PKP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PKP1 Gene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Name: Plakophilin 1
Chromosome: CHR1: 201252579 -201302121
Locus: 1q32.1
CNTN2 Gene Summary
This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be associated with adult myoclonic epilepsy. [provided by RefSeq, Sep 2016]
Gene Name: Contactin 2
Chromosome: CHR1: 205012339 -205047171
Locus: 1q32.1
Gene Diseases
The CNTN2 PKP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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