CNPY3-TPO Fusion FISH Probe
The CNPY3-TPO Fusion FISH Probe is used to confirm a fusion of the CNPY3 and TPO genes. The fusion of the CNPY3 and TPO genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNPY3-TPO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-RERE | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-REOR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-REGO | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-REGR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-REAQ | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-ORRE | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-OROR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-ORGO | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GORE | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GOOR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GOGO | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GOGR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GRRE | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GROR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GRGO | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GRGR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-AQRE | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-AQOR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-AQGO | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-AQGR | 20 (40 μL) | 200 μL |
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| CNPY3-TPO-20-AQAQ | 20 (40 μL) | 200 μL |
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TPO Gene Summary
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Gene Name: Thyroid Peroxidase
Chromosome: CHR2: 1417232 -1546499
Locus: 2p25.3
CNPY3 Gene Summary
This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
Gene Name: Canopy FGF Signaling Regulator 3
Chromosome: CHR6: 42896859 -42907008
Locus: 6p21.1
Gene Diseases
The CNPY3 TPO Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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