CNOT2-SLCO1A2 Fusion FISH Probe
The CNOT2-SLCO1A2 Fusion FISH Probe is used to confirm a fusion of the CNOT2 and SLCO1A2 genes. The fusion of the CNOT2 and SLCO1A2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNOT2-SLCO1A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-RERE | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-REOR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-REGO | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-REGR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-REAQ | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-ORRE | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-OROR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-ORGO | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GORE | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GOOR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GOGO | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GOGR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GRRE | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GROR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GRGO | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GRGR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-AQRE | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-AQOR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-AQGO | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-AQGR | 20 (40 μL) | 200 μL |
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| CNOT2-SLCO1A2-20-AQAQ | 20 (40 μL) | 200 μL |
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CNOT2 Gene Summary
This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: CCR4-NOT Transcription Complex Subunit 2
Chromosome: CHR12: 70636773 -70748773
Locus: 12q15
SLCO1A2 Gene Summary
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: Solute Carrier Organic Anion Transporter Family Member 1A2
Chromosome: CHR12: 21417533 -21548371
Locus: 12p12.1
Gene Diseases
The CNOT2 SLCO1A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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