CNOT1-GOT2 Fusion FISH Probe
The CNOT1-GOT2 Fusion FISH Probe is used to confirm a fusion of the CNOT1 and GOT2 genes. The fusion of the CNOT1 and GOT2 genes has been associated with Lung Squamous Cell Carcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNOT1-GOT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-RERE | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-REOR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-REGO | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-REGR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-REAQ | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-ORRE | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-OROR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-ORGO | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GORE | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GOOR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GOGO | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GOGR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GRRE | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GROR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GRGO | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GRGR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-AQRE | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-AQOR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-AQGO | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-AQGR | 20 (40 μL) | 200 μL |
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| CNOT1-GOT2-20-AQAQ | 20 (40 μL) | 200 μL |
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GOT2 Gene Summary
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Gene Name: Glutamic-oxaloacetic Transaminase 2
Chromosome: CHR16: 58741034 -58768246
Locus: 16q21
CNOT1 Gene Summary
The CCR4-NOT Transcription Complex Subunit 1 (CNOT1) gene is located on chr16 :58553854-58663750 at 16q21.
Gene Name: CCR4-NOT Transcription Complex Subunit 1
Chromosome: CHR16: 58553854 -58663750
Locus: 16q21
Gene Diseases
The CNOT1 GOT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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