CNN2-WDR18 Fusion FISH Probe
The CNN2-WDR18 Fusion FISH Probe is used to confirm a fusion of the CNN2 and WDR18 genes. The fusion of the CNN2 and WDR18 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNN2-WDR18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-RERE | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-REOR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-REGO | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-REGR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-REAQ | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-ORRE | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-OROR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-ORGO | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GORE | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GOOR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GOGO | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GOGR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GRRE | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GROR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GRGO | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GRGR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-AQRE | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-AQOR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-AQGO | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-AQGR | 20 (40 μL) | 200 μL |
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| CNN2-WDR18-20-AQAQ | 20 (40 μL) | 200 μL |
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CNN2 Gene Summary
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Gene Name: Calponin 2
Chromosome: CHR19: 1026297 -1039064
Locus: 19p13.3
WDR18 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 18
Chromosome: CHR19: 984327 -994569
Locus: 19p13.3
Gene Diseases
The CNN2 WDR18 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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