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CNN1-CBS Fusion FISH Probe

The CNN1-CBS Fusion FISH Probe is used to confirm a fusion of the CNN1 and CBS genes. The fusion of the CNN1 and CBS genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CNN1-CBS-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CNN1-CBS-20-RERE 20 (40 μL) 200 μL
CNN1-CBS-20-REOR 20 (40 μL) 200 μL
CNN1-CBS-20-REGO 20 (40 μL) 200 μL
CNN1-CBS-20-REGR 20 (40 μL) 200 μL
CNN1-CBS-20-REAQ 20 (40 μL) 200 μL
CNN1-CBS-20-ORRE 20 (40 μL) 200 μL
CNN1-CBS-20-OROR 20 (40 μL) 200 μL
CNN1-CBS-20-ORGO 20 (40 μL) 200 μL
CNN1-CBS-20-ORAQ 20 (40 μL) 200 μL
CNN1-CBS-20-GORE 20 (40 μL) 200 μL
CNN1-CBS-20-GOOR 20 (40 μL) 200 μL
CNN1-CBS-20-GOGO 20 (40 μL) 200 μL
CNN1-CBS-20-GOGR 20 (40 μL) 200 μL
CNN1-CBS-20-GOAQ 20 (40 μL) 200 μL
CNN1-CBS-20-GRRE 20 (40 μL) 200 μL
CNN1-CBS-20-GROR 20 (40 μL) 200 μL
CNN1-CBS-20-GRGO 20 (40 μL) 200 μL
CNN1-CBS-20-GRGR 20 (40 μL) 200 μL
CNN1-CBS-20-GRAQ 20 (40 μL) 200 μL
CNN1-CBS-20-AQRE 20 (40 μL) 200 μL
CNN1-CBS-20-AQOR 20 (40 μL) 200 μL
CNN1-CBS-20-AQGO 20 (40 μL) 200 μL
CNN1-CBS-20-AQGR 20 (40 μL) 200 μL
CNN1-CBS-20-AQAQ 20 (40 μL) 200 μL

CBS Gene Summary

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Gene Name: Cystathionine-beta-synthase

Chromosome: CHR21: 44473300 -44496472

Locus: 21q22.3

CNN1 Gene Summary

The Calponin 1 (CNN1) gene is located on chr19 :11649578-11661138 at 19p13.2.

Gene Name: Calponin 1

Chromosome: CHR19: 11649578 -11661138

Locus: 19p13.2

Gene Diseases

The CNN1 CBS Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.