CNKSR3-FBXO5 Fusion FISH Probe
The CNKSR3-FBXO5 Fusion FISH Probe is used to confirm a fusion of the CNKSR3 and FBXO5 genes. The fusion of the CNKSR3 and FBXO5 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNKSR3-FBXO5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-RERE | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-REOR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-REGO | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-REGR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-REAQ | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-ORRE | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-OROR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-ORGO | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GORE | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GOOR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GOGO | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GOGR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GRRE | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GROR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GRGO | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GRGR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-AQRE | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-AQOR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-AQGO | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-AQGR | 20 (40 μL) | 200 μL |
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| CNKSR3-FBXO5-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXO5 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008]
Gene Name: F-box Protein 5
Chromosome: CHR6: 153291657 -153304740
Locus: 6q25.2
CNKSR3 Gene Summary
The CNKSR Family Member 3 (CNKSR3) gene is located on chr6 :154726432-154831753 at 6q25.2.
Gene Name: CNKSR Family Member 3
Chromosome: CHR6: 154726432 -154831753
Locus: 6q25.2
Gene Diseases
The CNKSR3 FBXO5 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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