CNIH2-MS4A4A Fusion FISH Probe
The CNIH2-MS4A4A Fusion FISH Probe is used to confirm a fusion of the CNIH2 and MS4A4A genes. The fusion of the CNIH2 and MS4A4A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNIH2-MS4A4A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-RERE | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-REOR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-REGO | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-REGR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-REAQ | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-ORRE | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-OROR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-ORGO | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GORE | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GOOR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GOGO | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GOGR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GRRE | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GROR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GRGO | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GRGR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-AQRE | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-AQOR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-AQGO | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-AQGR | 20 (40 μL) | 200 μL |
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| CNIH2-MS4A4A-20-AQAQ | 20 (40 μL) | 200 μL |
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MS4A4A Gene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Membrane Spanning 4-domains A4A
Chromosome: CHR11: 60048013 -60076445
Locus: 11q12.2
CNIH2 Gene Summary
The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Cornichon Family AMPA Receptor Auxiliary Protein 2
Chromosome: CHR11: 66045695 -66051683
Locus: 11q13.2
Gene Diseases
The CNIH2 MS4A4A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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