CNBP-ALDH1L1 Fusion FISH Probe
The CNBP-ALDH1L1 Fusion FISH Probe is used to confirm a fusion of the CNBP and ALDH1L1 genes. The fusion of the CNBP and ALDH1L1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNBP-ALDH1L1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-RERE | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-REOR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-REGO | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-REGR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-REAQ | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-ORRE | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-OROR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-ORGO | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GORE | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GOOR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GOGO | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GOGR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GRRE | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GROR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GRGO | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GRGR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-AQRE | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-AQOR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-AQGO | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-AQGR | 20 (40 μL) | 200 μL |
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| CNBP-ALDH1L1-20-AQAQ | 20 (40 μL) | 200 μL |
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CNBP Gene Summary
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
Gene Name: CCHC-type Zinc Finger Nucleic Acid Binding Protein
Chromosome: CHR3: 128886657 -128902810
Locus: 3q21.3
ALDH1L1 Gene Summary
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Aldehyde Dehydrogenase 1 Family Member L1
Chromosome: CHR3: 125822407 -125899485
Locus: 3q21.3
Gene Diseases
The CNBP ALDH1L1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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