CNBD1-PTPN2 Fusion FISH Probe
The CNBD1-PTPN2 Fusion FISH Probe is used to confirm a fusion of the CNBD1 and PTPN2 genes. The fusion of the CNBD1 and PTPN2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNBD1-PTPN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-RERE | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-REOR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-REGO | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-REGR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-REAQ | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-ORRE | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-OROR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-ORGO | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GORE | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GOOR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GOGO | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GOGR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GRRE | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GROR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GRGO | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GRGR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-AQRE | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-AQOR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-AQGO | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-AQGR | 20 (40 μL) | 200 μL |
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| CNBD1-PTPN2-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPN2 Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 2
Chromosome: CHR18: 12785476 -12884334
Locus: 18p11.21
CNBD1 Gene Summary
The Cyclic Nucleotide Binding Domain Containing 1 (CNBD1) gene is located on chr8 :87878675-88394955 at 8q21.3.
Gene Name: Cyclic Nucleotide Binding Domain Containing 1
Chromosome: CHR8: 87878675 -88394955
Locus: 8q21.3
Gene Diseases
The CNBD1 PTPN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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