CLU-SF3B2 Fusion FISH Probe
The CLU-SF3B2 Fusion FISH Probe is used to confirm a fusion of the CLU and SF3B2 genes. The fusion of the CLU and SF3B2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLU-SF3B2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-RERE | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-REOR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-REGO | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-REGR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-REAQ | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-ORRE | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-OROR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-ORGO | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GORE | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GOOR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GOGO | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GOGR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GRRE | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GROR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GRGO | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GRGR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-AQRE | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-AQOR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-AQGO | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-AQGR | 20 (40 μL) | 200 μL |
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| CLU-SF3B2-20-AQAQ | 20 (40 μL) | 200 μL |
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CLU Gene Summary
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Gene Name: Clusterin
Chromosome: CHR8: 27454433 -27472328
Locus: 8p21.1
SF3B2 Gene Summary
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
Gene Name: Splicing Factor 3b Subunit 2
Chromosome: CHR11: 65819815 -65836382
Locus: 11q13.1
Gene Diseases
The CLU SF3B2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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