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CLU-SF3B2 Fusion FISH Probe

The CLU-SF3B2 Fusion FISH Probe is used to confirm a fusion of the CLU and SF3B2 genes. The fusion of the CLU and SF3B2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CLU-SF3B2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CLU-SF3B2-20-RERE 20 (40 μL) 200 μL
CLU-SF3B2-20-REOR 20 (40 μL) 200 μL
CLU-SF3B2-20-REGO 20 (40 μL) 200 μL
CLU-SF3B2-20-REGR 20 (40 μL) 200 μL
CLU-SF3B2-20-REAQ 20 (40 μL) 200 μL
CLU-SF3B2-20-ORRE 20 (40 μL) 200 μL
CLU-SF3B2-20-OROR 20 (40 μL) 200 μL
CLU-SF3B2-20-ORGO 20 (40 μL) 200 μL
CLU-SF3B2-20-ORAQ 20 (40 μL) 200 μL
CLU-SF3B2-20-GORE 20 (40 μL) 200 μL
CLU-SF3B2-20-GOOR 20 (40 μL) 200 μL
CLU-SF3B2-20-GOGO 20 (40 μL) 200 μL
CLU-SF3B2-20-GOGR 20 (40 μL) 200 μL
CLU-SF3B2-20-GOAQ 20 (40 μL) 200 μL
CLU-SF3B2-20-GRRE 20 (40 μL) 200 μL
CLU-SF3B2-20-GROR 20 (40 μL) 200 μL
CLU-SF3B2-20-GRGO 20 (40 μL) 200 μL
CLU-SF3B2-20-GRGR 20 (40 μL) 200 μL
CLU-SF3B2-20-GRAQ 20 (40 μL) 200 μL
CLU-SF3B2-20-AQRE 20 (40 μL) 200 μL
CLU-SF3B2-20-AQOR 20 (40 μL) 200 μL
CLU-SF3B2-20-AQGO 20 (40 μL) 200 μL
CLU-SF3B2-20-AQGR 20 (40 μL) 200 μL
CLU-SF3B2-20-AQAQ 20 (40 μL) 200 μL

CLU Gene Summary

The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]

Gene Name: Clusterin

Chromosome: CHR8: 27454433 -27472328

Locus: 8p21.1

SF3B2 Gene Summary

This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]

Gene Name: Splicing Factor 3b Subunit 2

Chromosome: CHR11: 65819815 -65836382

Locus: 11q13.1

Gene Diseases

The CLU SF3B2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.