CLU-SEC63 Fusion FISH Probe
The CLU-SEC63 Fusion FISH Probe is used to confirm a fusion of the CLU and SEC63 genes. The fusion of the CLU and SEC63 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLU-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-RERE | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-REOR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-REGO | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-REGR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-OROR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GORE | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GROR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
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| CLU-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
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CLU Gene Summary
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Gene Name: Clusterin
Chromosome: CHR8: 27454433 -27472328
Locus: 8p21.1
SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
Gene Diseases
The CLU SEC63 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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