CLU-PPP1R12B Fusion FISH Probe
The CLU-PPP1R12B Fusion FISH Probe is used to confirm a fusion of the CLU and PPP1R12B genes. The fusion of the CLU and PPP1R12B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLU-PPP1R12B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-RERE | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-REOR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-REGO | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-REGR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-REAQ | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-ORRE | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-OROR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-ORGO | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GORE | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GOOR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GOGO | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GOGR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GRRE | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GROR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GRGO | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GRGR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-AQRE | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-AQOR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-AQGO | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-AQGR | 20 (40 μL) | 200 μL |
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| CLU-PPP1R12B-20-AQAQ | 20 (40 μL) | 200 μL |
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CLU Gene Summary
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Gene Name: Clusterin
Chromosome: CHR8: 27454433 -27472328
Locus: 8p21.1
PPP1R12B Gene Summary
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 12B
Chromosome: CHR1: 202317829 -202557697
Locus: 1q32.1
Gene Diseases
The CLU PPP1R12B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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