CLTA-UBE2R2 Fusion FISH Probe
The CLTA-UBE2R2 Fusion FISH Probe is used to confirm a fusion of the CLTA and UBE2R2 genes. The fusion of the CLTA and UBE2R2 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLTA-UBE2R2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-RERE | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-REOR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-REGO | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-REGR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-REAQ | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-ORRE | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-OROR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-ORGO | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GORE | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GOOR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GOGO | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GOGR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GRRE | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GROR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GRGO | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GRGR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-AQRE | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-AQOR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-AQGO | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-AQGR | 20 (40 μL) | 200 μL |
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| CLTA-UBE2R2-20-AQAQ | 20 (40 μL) | 200 μL |
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CLTA Gene Summary
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010]
Gene Name: Clathrin Light Chain A
Chromosome: CHR9: 36190852 -36212059
Locus: 9p13.3
UBE2R2 Gene Summary
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 R2
Chromosome: CHR9: 33817181 -33920401
Locus: 9p13.3
Gene Diseases
The CLTA UBE2R2 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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