CLSTN1-PLEKHG5 Fusion FISH Probe
The CLSTN1-PLEKHG5 Fusion FISH Probe is used to confirm a fusion of the CLSTN1 and PLEKHG5 genes. The fusion of the CLSTN1 and PLEKHG5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLSTN1-PLEKHG5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-RERE | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-REOR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-REGO | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-REGR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-REAQ | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-ORRE | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-OROR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-ORGO | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GORE | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GOOR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GOGO | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GOGR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GRRE | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GROR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GRGO | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GRGR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-AQRE | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-AQOR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-AQGO | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-AQGR | 20 (40 μL) | 200 μL |
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| CLSTN1-PLEKHG5-20-AQAQ | 20 (40 μL) | 200 μL |
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CLSTN1 Gene Summary
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: Calsyntenin 1
Chromosome: CHR1: 9789078 -9884550
Locus: 1p36.22
PLEKHG5 Gene Summary
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Pleckstrin Homology And RhoGEF Domain Containing G5
Chromosome: CHR1: 6526151 -6580069
Locus: 1p36.31
Gene Diseases
The CLSTN1 PLEKHG5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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