CLSTN1-CTNNBIP1 Fusion FISH Probe
The CLSTN1-CTNNBIP1 Fusion FISH Probe is used to confirm a fusion of the CLSTN1 and CTNNBIP1 genes. The fusion of the CLSTN1 and CTNNBIP1 genes has been associated with Lung Adenocarcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLSTN1-CTNNBIP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CLSTN1-CTNNBIP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
CLSTN1 Gene Summary
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: Calsyntenin 1
Chromosome: CHR1: 9789078 -9884550
Locus: 1p36.22
CTNNBIP1 Gene Summary
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Catenin Beta Interacting Protein 1
Chromosome: CHR1: 9908333 -9970316
Locus: 1p36.22
Gene Diseases
The CLSTN1 CTNNBIP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|