CLPTM1L-PDCD6 Fusion FISH Probe
The CLPTM1L-PDCD6 Fusion FISH Probe is used to confirm a fusion of the CLPTM1L and PDCD6 genes. The fusion of the CLPTM1L and PDCD6 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLPTM1L-PDCD6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-RERE | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-REOR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-REGO | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-REGR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-REAQ | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-ORRE | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-OROR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-ORGO | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GORE | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GOOR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GOGO | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GOGR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GRRE | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GROR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GRGO | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GRGR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-AQRE | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-AQOR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-AQGO | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-AQGR | 20 (40 μL) | 200 μL |
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| CLPTM1L-PDCD6-20-AQAQ | 20 (40 μL) | 200 μL |
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PDCD6 Gene Summary
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
Gene Name: Programmed Cell Death 6
Chromosome: CHR5: 271735 -315089
Locus: 5p15.33
CLPTM1L Gene Summary
The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015]
Gene Name: CLPTM1 Like
Chromosome: CHR5: 1317999 -1345002
Locus: 5p15.33
Gene Diseases
The CLPTM1L PDCD6 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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