CLPB-MTUS2 Fusion FISH Probe
The CLPB-MTUS2 Fusion FISH Probe is used to confirm a fusion of the CLPB and MTUS2 genes. The fusion of the CLPB and MTUS2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLPB-MTUS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-RERE | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-REOR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-REGO | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-REGR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-REAQ | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-ORRE | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-OROR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-ORGO | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GORE | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GOOR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GOGO | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GOGR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GRRE | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GROR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GRGO | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GRGR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-AQRE | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-AQOR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-AQGO | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-AQGR | 20 (40 μL) | 200 μL |
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| CLPB-MTUS2-20-AQAQ | 20 (40 μL) | 200 μL |
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MTUS2 Gene Summary
The Microtubule Associated Scaffold Protein 2 (MTUS2) gene is located on chr13 :29598747-30080084 at 13q12.3.
Gene Name: Microtubule Associated Scaffold Protein 2
Chromosome: CHR13: 29598747 -30080084
Locus: 13q12.3
CLPB Gene Summary
This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: ClpB Homolog, Mitochondrial AAA ATPase Chaperonin
Chromosome: CHR11: 72003469 -72145568
Locus: 11q13.4
Gene Diseases
The CLPB MTUS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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