CLN6-FBXL17 Fusion FISH Probe
The CLN6-FBXL17 Fusion FISH Probe is used to confirm a fusion of the CLN6 and FBXL17 genes. The fusion of the CLN6 and FBXL17 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLN6-FBXL17-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CLN6-FBXL17-20-AQAQ | 20 (40 μL) | 200 μL |
|
CLN6 Gene Summary
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]
Gene Name: CLN6, Transmembrane ER Protein
Chromosome: CHR15: 68499329 -68522080
Locus: 15q23
FBXL17 Gene Summary
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box And Leucine Rich Repeat Protein 17
Chromosome: CHR5: 107194733 -107717799
Locus: 5q21.3
Gene Diseases
The CLN6 FBXL17 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|