CLIP2-RORB Fusion FISH Probe
The CLIP2-RORB Fusion FISH Probe is used to confirm a fusion of the CLIP2 and RORB genes. The fusion of the CLIP2 and RORB genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLIP2-RORB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-RERE | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-REOR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-REGO | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-REGR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-REAQ | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-ORRE | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-OROR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-ORGO | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GORE | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GOOR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GOGO | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GOGR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GRRE | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GROR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GRGO | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GRGR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-AQRE | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-AQOR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-AQGO | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-AQGR | 20 (40 μL) | 200 μL |
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| CLIP2-RORB-20-AQAQ | 20 (40 μL) | 200 μL |
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RORB Gene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Gene Name: RAR Related Orphan Receptor B
Chromosome: CHR9: 77112251 -77302117
Locus: 9q21.13
CLIP2 Gene Summary
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: CAP-Gly Domain Containing Linker Protein 2
Chromosome: CHR7: 73703804 -73820273
Locus: 7q11.23
Gene Diseases
The CLIP2 RORB Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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