CLIC4-ARFGAP3 Fusion FISH Probe
The CLIC4-ARFGAP3 Fusion FISH Probe is used to confirm a fusion of the CLIC4 and ARFGAP3 genes. The fusion of the CLIC4 and ARFGAP3 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLIC4-ARFGAP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-RERE | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-REOR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-REGO | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-REGR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-REAQ | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-ORRE | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-OROR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-ORGO | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GORE | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GOOR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GOGO | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GOGR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GRRE | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GROR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GRGO | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GRGR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-AQRE | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-AQOR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-AQGO | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-AQGR | 20 (40 μL) | 200 μL |
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| CLIC4-ARFGAP3-20-AQAQ | 20 (40 μL) | 200 μL |
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CLIC4 Gene Summary
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). [provided by RefSeq, Jul 2008]
Gene Name: Chloride Intracellular Channel 4
Chromosome: CHR1: 25071759 -25170815
Locus: 1p36.11
ARFGAP3 Gene Summary
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
Gene Name: ADP Ribosylation Factor GTPase Activating Protein 3
Chromosome: CHR22: 43192531 -43253408
Locus: 22q13.2
Gene Diseases
The CLIC4 ARFGAP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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