CLEC16A-LITAF Fusion FISH Probe
The CLEC16A-LITAF Fusion FISH Probe is used to confirm a fusion of the CLEC16A and LITAF genes. The fusion of the CLEC16A and LITAF genes has been associated with Breast Invasive Carcinoma, and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLEC16A-LITAF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-RERE | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-REOR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-REGO | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-REGR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-REAQ | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-ORRE | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-OROR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-ORGO | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-ORAQ | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GORE | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GOOR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GOGO | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GOGR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GOAQ | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GRRE | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GROR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GRGO | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GRGR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-GRAQ | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-AQRE | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-AQOR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-AQGO | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-AQGR | 20 (40 μL) | 200 μL |
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| CLEC16A-LITAF-20-AQAQ | 20 (40 μL) | 200 μL |
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LITAF Gene Summary
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
Gene Name: Lipopolysaccharide Induced TNF Factor
Chromosome: CHR16: 11641577 -11681322
Locus: 16p13.13
CLEC16A Gene Summary
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: C-type Lectin Domain Containing 16A
Chromosome: CHR16: 11038344 -11276046
Locus: 16p13.13
Gene Diseases
The CLEC16A LITAF Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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