CKB-SUPT16H Fusion FISH Probe
The CKB-SUPT16H Fusion FISH Probe is used to confirm a fusion of the CKB and SUPT16H genes. The fusion of the CKB and SUPT16H genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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CKB-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-RERE | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-REOR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-REGO | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-REGR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-OROR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GORE | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GROR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL | ||
CKB-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
CKB Gene Summary
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Creatine Kinase B
Chromosome: CHR14: 103985995 -103989170
Locus: 14q32.33
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The CKB SUPT16H Fusion has been associated with the following diseases:
Disease Name |
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Colon Adenocarcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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