CISD1-GABRA1 Fusion FISH Probe
The CISD1-GABRA1 Fusion FISH Probe is used to confirm a fusion of the CISD1 and GABRA1 genes. The fusion of the CISD1 and GABRA1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CISD1-GABRA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-RERE | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-REOR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-REGO | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-REGR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-REAQ | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-ORRE | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-OROR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-ORGO | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GORE | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GOOR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GOGO | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GOGR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GRRE | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GROR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GRGO | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GRGR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-AQRE | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-AQOR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-AQGO | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-AQGR | 20 (40 μL) | 200 μL |
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| CISD1-GABRA1-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRA1 Gene Summary
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Alpha1 Subunit
Chromosome: CHR5: 161274196 -161326965
Locus: 5q34
CISD1 Gene Summary
This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
Gene Name: CDGSH Iron Sulfur Domain 1
Chromosome: CHR10: 60028894 -60049019
Locus: 10q21.1
Gene Diseases
The CISD1 GABRA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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