CHSY3-DDX46 Fusion FISH Probe
The CHSY3-DDX46 Fusion FISH Probe is used to confirm a fusion of the CHSY3 and DDX46 genes. The fusion of the CHSY3 and DDX46 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHSY3-DDX46-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-RERE | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-REOR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-REGO | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-REGR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-REAQ | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-ORRE | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-OROR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-ORGO | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GORE | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GOOR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GOGO | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GOGR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GRRE | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GROR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GRGO | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GRGR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-AQRE | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-AQOR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-AQGO | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-AQGR | 20 (40 μL) | 200 μL |
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| CHSY3-DDX46-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX46 Gene Summary
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: DEAD-box Helicase 46
Chromosome: CHR5: 134094460 -134166812
Locus: 5q31.1
CHSY3 Gene Summary
CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).[supplied by OMIM, Mar 2008]
Gene Name: Chondroitin Sulfate Synthase 3
Chromosome: CHR5: 129240522 -129522327
Locus: 5q23.3
Gene Diseases
The CHSY3 DDX46 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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