CHST8-PDCD5 Fusion FISH Probe
The CHST8-PDCD5 Fusion FISH Probe is used to confirm a fusion of the CHST8 and PDCD5 genes. The fusion of the CHST8 and PDCD5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHST8-PDCD5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-RERE | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-REOR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-REGO | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-REGR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-REAQ | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-ORRE | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-OROR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-ORGO | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GORE | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GOOR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GOGO | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GOGR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GRRE | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GROR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GRGO | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GRGR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-AQRE | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-AQOR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-AQGO | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-AQGR | 20 (40 μL) | 200 μL |
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| CHST8-PDCD5-20-AQAQ | 20 (40 μL) | 200 μL |
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PDCD5 Gene Summary
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]
Gene Name: Programmed Cell Death 5
Chromosome: CHR19: 33072093 -33078358
Locus: 19q13.11
CHST8 Gene Summary
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Carbohydrate Sulfotransferase 8
Chromosome: CHR19: 34112860 -34264414
Locus: 19q13.11
Gene Diseases
The CHST8 PDCD5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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