CHST11-RFX4 Fusion FISH Probe
The CHST11-RFX4 Fusion FISH Probe is used to confirm a fusion of the CHST11 and RFX4 genes. The fusion of the CHST11 and RFX4 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHST11-RFX4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CHST11-RFX4-20-AQAQ | 20 (40 μL) | 200 μL |
|
RFX4 Gene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Gene Name: Regulatory Factor X4
Chromosome: CHR12: 106976684 -107156582
Locus: 12q23.3
CHST11 Gene Summary
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Carbohydrate Sulfotransferase 11
Chromosome: CHR12: 104850691 -105155792
Locus: 12q23.3
Gene Diseases
The CHST11 RFX4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|