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CHST11-HCFC2 Fusion FISH Probe

The CHST11-HCFC2 Fusion FISH Probe is used to confirm a fusion of the CHST11 and HCFC2 genes. The fusion of the CHST11 and HCFC2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CHST11-HCFC2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CHST11-HCFC2-20-RERE 20 (40 μL) 200 μL
CHST11-HCFC2-20-REOR 20 (40 μL) 200 μL
CHST11-HCFC2-20-REGO 20 (40 μL) 200 μL
CHST11-HCFC2-20-REGR 20 (40 μL) 200 μL
CHST11-HCFC2-20-REAQ 20 (40 μL) 200 μL
CHST11-HCFC2-20-ORRE 20 (40 μL) 200 μL
CHST11-HCFC2-20-OROR 20 (40 μL) 200 μL
CHST11-HCFC2-20-ORGO 20 (40 μL) 200 μL
CHST11-HCFC2-20-ORAQ 20 (40 μL) 200 μL
CHST11-HCFC2-20-GORE 20 (40 μL) 200 μL
CHST11-HCFC2-20-GOOR 20 (40 μL) 200 μL
CHST11-HCFC2-20-GOGO 20 (40 μL) 200 μL
CHST11-HCFC2-20-GOGR 20 (40 μL) 200 μL
CHST11-HCFC2-20-GOAQ 20 (40 μL) 200 μL
CHST11-HCFC2-20-GRRE 20 (40 μL) 200 μL
CHST11-HCFC2-20-GROR 20 (40 μL) 200 μL
CHST11-HCFC2-20-GRGO 20 (40 μL) 200 μL
CHST11-HCFC2-20-GRGR 20 (40 μL) 200 μL
CHST11-HCFC2-20-GRAQ 20 (40 μL) 200 μL
CHST11-HCFC2-20-AQRE 20 (40 μL) 200 μL
CHST11-HCFC2-20-AQOR 20 (40 μL) 200 μL
CHST11-HCFC2-20-AQGO 20 (40 μL) 200 μL
CHST11-HCFC2-20-AQGR 20 (40 μL) 200 μL
CHST11-HCFC2-20-AQAQ 20 (40 μL) 200 μL

HCFC2 Gene Summary

This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]

Gene Name: Host Cell Factor C2

Chromosome: CHR12: 104458235 -104500304

Locus: 12q23.3

CHST11 Gene Summary

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Gene Name: Carbohydrate Sulfotransferase 11

Chromosome: CHR12: 104850691 -105155792

Locus: 12q23.3

Gene Diseases

The CHST11 HCFC2 Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.