CHST11-HCFC2 Fusion FISH Probe
The CHST11-HCFC2 Fusion FISH Probe is used to confirm a fusion of the CHST11 and HCFC2 genes. The fusion of the CHST11 and HCFC2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHST11-HCFC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-RERE | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-REOR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-REGO | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-REGR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-REAQ | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-ORRE | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-OROR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-ORGO | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GORE | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GOOR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GOGO | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GOGR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GRRE | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GROR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GRGO | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GRGR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-AQRE | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-AQOR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-AQGO | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-AQGR | 20 (40 μL) | 200 μL |
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| CHST11-HCFC2-20-AQAQ | 20 (40 μL) | 200 μL |
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HCFC2 Gene Summary
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]
Gene Name: Host Cell Factor C2
Chromosome: CHR12: 104458235 -104500304
Locus: 12q23.3
CHST11 Gene Summary
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Carbohydrate Sulfotransferase 11
Chromosome: CHR12: 104850691 -105155792
Locus: 12q23.3
Gene Diseases
The CHST11 HCFC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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