CHMP1A-FANCA Fusion FISH Probe
The CHMP1A-FANCA Fusion FISH Probe is used to confirm a fusion of the CHMP1A and FANCA genes. The fusion of the CHMP1A and FANCA genes has been associated with Stomach Adenocarcinoma, and Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHMP1A-FANCA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-RERE | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-REOR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-REGO | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-REGR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-REAQ | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-ORRE | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-OROR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-ORGO | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GORE | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GOOR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GOGO | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GOGR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GRRE | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GROR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GRGO | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GRGR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-AQRE | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-AQOR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-AQGO | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-AQGR | 20 (40 μL) | 200 μL |
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| CHMP1A-FANCA-20-AQAQ | 20 (40 μL) | 200 μL |
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FANCA Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008]
Gene Name: Fanconi Anemia Complementation Group A
Chromosome: CHR16: 89803958 -89883065
Locus: 16q24.3
CHMP1A Gene Summary
This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Charged Multivesicular Body Protein 1A
Chromosome: CHR16: 89710843 -89724129
Locus: 16q24.3
Gene Diseases
The CHMP1A FANCA Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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