CHKA-PAK1 Fusion FISH Probe
The CHKA-PAK1 Fusion FISH Probe is used to confirm a fusion of the CHKA and PAK1 genes. The fusion of the CHKA and PAK1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHKA-PAK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CHKA-PAK1-20-AQAQ | 20 (40 μL) | 200 μL |
|
CHKA Gene Summary
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Choline Kinase Alpha
Chromosome: CHR11: 67820325 -67888858
Locus: 11q13.2
PAK1 Gene Summary
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Name: P21 (RAC1) Activated Kinase 1
Chromosome: CHR11: 77033059 -77185108
Locus: 11q13.5-q14.1
Gene Diseases
The CHKA PAK1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|