CHKA-HNF1B Fusion FISH Probe
The CHKA-HNF1B Fusion FISH Probe is used to confirm a fusion of the CHKA and HNF1B genes. The fusion of the CHKA and HNF1B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHKA-HNF1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-RERE | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-REOR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-REGO | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-REGR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-REAQ | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-ORRE | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-OROR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-ORGO | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GORE | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GOOR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GOGO | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GOGR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GRRE | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GROR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GRGO | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GRGR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-AQRE | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-AQOR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-AQGO | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-AQGR | 20 (40 μL) | 200 μL |
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| CHKA-HNF1B-20-AQAQ | 20 (40 μL) | 200 μL |
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CHKA Gene Summary
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Choline Kinase Alpha
Chromosome: CHR11: 67820325 -67888858
Locus: 11q13.2
HNF1B Gene Summary
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: HNF1 Homeobox B
Chromosome: CHR17: 36046433 -36105096
Locus: 17q12
Gene Diseases
The CHKA HNF1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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