CHD8-TOX4 Fusion FISH Probe
The CHD8-TOX4 Fusion FISH Probe is used to confirm a fusion of the CHD8 and TOX4 genes. The fusion of the CHD8 and TOX4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD8-TOX4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-RERE | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-REOR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-REGO | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-REGR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-OROR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GORE | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GROR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD8-TOX4-20-AQAQ | 20 (40 μL) | 200 μL |
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TOX4 Gene Summary
The TOX High Mobility Group Box Family Member 4 (TOX4) gene is located on chr14 :21945334-21967319 at 14q11.2.
Gene Name: TOX High Mobility Group Box Family Member 4
Chromosome: CHR14: 21945334 -21967319
Locus: 14q11.2
CHD8 Gene Summary
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Gene Name: Chromodomain Helicase DNA Binding Protein 8
Chromosome: CHR14: 21853352 -21905457
Locus: 14q11.2
Gene Diseases
The CHD8 TOX4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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