CHD8-RAB2B Fusion FISH Probe
The CHD8-RAB2B Fusion FISH Probe is used to confirm a fusion of the CHD8 and RAB2B genes. The fusion of the CHD8 and RAB2B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD8-RAB2B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-RERE | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-REOR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-REGO | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-REGR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-OROR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GORE | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GROR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD8-RAB2B-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD8 Gene Summary
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Gene Name: Chromodomain Helicase DNA Binding Protein 8
Chromosome: CHR14: 21853352 -21905457
Locus: 14q11.2
RAB2B Gene Summary
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
Gene Name: RAB2B, Member RAS Oncogene Family
Chromosome: CHR14: 21927178 -21945132
Locus: 14q11.2
Gene Diseases
The CHD8 RAB2B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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