CHD8-AP1S1 Fusion FISH Probe
The CHD8-AP1S1 Fusion FISH Probe is used to confirm a fusion of the CHD8 and AP1S1 genes. The fusion of the CHD8 and AP1S1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD8-AP1S1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-RERE | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-REOR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-REGO | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-REGR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-OROR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GORE | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GROR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD8-AP1S1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP1S1 Gene Summary
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 1 Sigma 1 Subunit
Chromosome: CHR7: 100797685 -100804557
Locus: 7q22.1
CHD8 Gene Summary
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Gene Name: Chromodomain Helicase DNA Binding Protein 8
Chromosome: CHR14: 21853352 -21905457
Locus: 14q11.2
Gene Diseases
The CHD8 AP1S1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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