CHD6-WFDC11 Fusion FISH Probe
The CHD6-WFDC11 Fusion FISH Probe is used to confirm a fusion of the CHD6 and WFDC11 genes. The fusion of the CHD6 and WFDC11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD6-WFDC11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-RERE | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-REOR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-REGO | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-REGR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-OROR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GORE | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GROR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD6-WFDC11-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD6 Gene Summary
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Gene Name: Chromodomain Helicase DNA Binding Protein 6
Chromosome: CHR20: 40031169 -40247133
Locus: 20q12
WFDC11 Gene Summary
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. [provided by RefSeq, Jul 2008]
Gene Name: WAP Four-disulfide Core Domain 11
Chromosome: CHR20: 44277201 -44298878
Locus: 20q13.12
Gene Diseases
The CHD6 WFDC11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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