CHD6-PTPRT Fusion FISH Probe
The CHD6-PTPRT Fusion FISH Probe is used to confirm a fusion of the CHD6 and PTPRT genes. The fusion of the CHD6 and PTPRT genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD6-PTPRT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-RERE | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-REOR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-REGO | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-REGR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-OROR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GORE | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GROR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD6-PTPRT-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRT Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type T
Chromosome: CHR20: 40701391 -41818557
Locus: 20q12-q13.11
CHD6 Gene Summary
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Gene Name: Chromodomain Helicase DNA Binding Protein 6
Chromosome: CHR20: 40031169 -40247133
Locus: 20q12
Gene Diseases
The CHD6 PTPRT Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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