CHD6-CTNNBL1 Fusion FISH Probe
The CHD6-CTNNBL1 Fusion FISH Probe is used to confirm a fusion of the CHD6 and CTNNBL1 genes. The fusion of the CHD6 and CTNNBL1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD6-CTNNBL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-RERE | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-REOR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-REGO | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-REGR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-OROR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GORE | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GROR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD6-CTNNBL1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNBL1 Gene Summary
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
Gene Name: Catenin Beta Like 1
Chromosome: CHR20: 36322433 -36500520
Locus: 20q11.23
CHD6 Gene Summary
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Gene Name: Chromodomain Helicase DNA Binding Protein 6
Chromosome: CHR20: 40031169 -40247133
Locus: 20q12
Gene Diseases
The CHD6 CTNNBL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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