CHD6-ABHD12 Fusion FISH Probe
The CHD6-ABHD12 Fusion FISH Probe is used to confirm a fusion of the CHD6 and ABHD12 genes. The fusion of the CHD6 and ABHD12 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD6-ABHD12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-RERE | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-REOR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-REGO | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-REGR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-OROR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GORE | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GROR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD6-ABHD12-20-AQAQ | 20 (40 μL) | 200 μL |
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ABHD12 Gene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
Gene Name: Abhydrolase Domain Containing 12
Chromosome: CHR20: 25275378 -25371618
Locus: 20p11.21
CHD6 Gene Summary
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Gene Name: Chromodomain Helicase DNA Binding Protein 6
Chromosome: CHR20: 40031169 -40247133
Locus: 20q12
Gene Diseases
The CHD6 ABHD12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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