CHD4-DTX1 Fusion FISH Probe
The CHD4-DTX1 Fusion FISH Probe is used to confirm a fusion of the CHD4 and DTX1 genes. The fusion of the CHD4 and DTX1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD4-DTX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-RERE | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-REOR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-REGO | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-REGR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-OROR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GORE | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GROR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD4-DTX1-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD4 Gene Summary
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Name: Chromodomain Helicase DNA Binding Protein 4
Chromosome: CHR12: 6679247 -6716551
Locus: 12p13.31
DTX1 Gene Summary
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008]
Gene Name: Deltex E3 Ubiquitin Ligase 1
Chromosome: CHR12: 113495661 -113535833
Locus: 12q24.13
Gene Diseases
The CHD4 DTX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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