CHD2-HOMER2 Fusion FISH Probe
The CHD2-HOMER2 Fusion FISH Probe is used to confirm a fusion of the CHD2 and HOMER2 genes. The fusion of the CHD2 and HOMER2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHD2-HOMER2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-RERE | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-REOR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-REGO | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-REGR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-REAQ | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-ORRE | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-OROR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-ORGO | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GORE | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GOOR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GOGO | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GROR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GRGR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-AQRE | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-AQOR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-AQGO | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-AQGR | 20 (40 μL) | 200 μL |
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| CHD2-HOMER2-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD2 Gene Summary
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Chromodomain Helicase DNA Binding Protein 2
Chromosome: CHR15: 93443550 -93571237
Locus: 15q26.1
HOMER2 Gene Summary
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011]
Gene Name: Homer Scaffolding Protein 2
Chromosome: CHR15: 83517728 -83621476
Locus: 15q25.2
Gene Diseases
The CHD2 HOMER2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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