CERK-SCUBE1 Fusion FISH Probe
The CERK-SCUBE1 Fusion FISH Probe is used to confirm a fusion of the CERK and SCUBE1 genes. The fusion of the CERK and SCUBE1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CERK-SCUBE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-RERE | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-REOR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-REGO | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-REGR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-REAQ | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-ORRE | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-OROR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-ORGO | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GORE | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GOOR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GOGO | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GOGR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GRRE | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GROR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GRGO | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GRGR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-AQRE | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-AQOR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-AQGO | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-AQGR | 20 (40 μL) | 200 μL |
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| CERK-SCUBE1-20-AQAQ | 20 (40 μL) | 200 μL |
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CERK Gene Summary
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]
Gene Name: Ceramide Kinase
Chromosome: CHR22: 47080306 -47134152
Locus: 22q13.31
SCUBE1 Gene Summary
This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
Gene Name: Signal Peptide, CUB Domain And EGF Like Domain Containing 1
Chromosome: CHR22: 43599228 -43739394
Locus: 22q13.2
Gene Diseases
The CERK SCUBE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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