CEP72-EXOC3 Fusion FISH Probe
The CEP72-EXOC3 Fusion FISH Probe is used to confirm a fusion of the CEP72 and EXOC3 genes. The fusion of the CEP72 and EXOC3 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEP72-EXOC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-RERE | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-REOR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-REGO | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-REGR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-REAQ | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-ORRE | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-OROR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-ORGO | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GORE | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GOOR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GOGO | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GOGR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GRRE | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GROR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GRGO | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GRGR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-AQRE | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-AQOR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-AQGO | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-AQGR | 20 (40 μL) | 200 μL |
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| CEP72-EXOC3-20-AQAQ | 20 (40 μL) | 200 μL |
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EXOC3 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 3
Chromosome: CHR5: 443333 -467409
Locus: 5p15.33
CEP72 Gene Summary
The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008]
Gene Name: Centrosomal Protein 72
Chromosome: CHR5: 612404 -653666
Locus: 5p15.33
Gene Diseases
The CEP72 EXOC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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