CEP70-TNFSF10 Fusion FISH Probe
The CEP70-TNFSF10 Fusion FISH Probe is used to confirm a fusion of the CEP70 and TNFSF10 genes. The fusion of the CEP70 and TNFSF10 genes has been associated with Prostate Adenocarcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEP70-TNFSF10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-RERE | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-REOR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-REGO | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-REGR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-REAQ | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-ORRE | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-OROR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-ORGO | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-ORAQ | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GORE | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GOOR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GOGO | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GOGR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GOAQ | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GRRE | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GROR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GRGO | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GRGR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-GRAQ | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-AQRE | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-AQOR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-AQGO | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-AQGR | 20 (40 μL) | 200 μL |
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| CEP70-TNFSF10-20-AQAQ | 20 (40 μL) | 200 μL |
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TNFSF10 Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Name: TNF Superfamily Member 10
Chromosome: CHR3: 172223297 -172241297
Locus: 3q26.31
CEP70 Gene Summary
The Centrosomal Protein 70 (CEP70) gene is located on chr3 :138213186-138313129 at 3q22.3.
Gene Name: Centrosomal Protein 70
Chromosome: CHR3: 138213186 -138313129
Locus: 3q22.3
Gene Diseases
The CEP70 TNFSF10 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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