CEP350-LEPROT Fusion FISH Probe
The CEP350-LEPROT Fusion FISH Probe is used to confirm a fusion of the CEP350 and LEPROT genes. The fusion of the CEP350 and LEPROT genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CEP350-LEPROT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CEP350-LEPROT-20-AQAQ | 20 (40 μL) | 200 μL |
|
CEP350 Gene Summary
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Centrosomal Protein 350
Chromosome: CHR1: 179923907 -180084015
Locus: 1q25.2
LEPROT Gene Summary
LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]
Gene Name: Leptin Receptor Overlapping Transcript
Chromosome: CHR1: 65886130 -65901690
Locus: 1p31.3
Gene Diseases
The CEP350 LEPROT Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|