CEP164-APOC3 Fusion FISH Probe
The CEP164-APOC3 Fusion FISH Probe is used to confirm a fusion of the CEP164 and APOC3 genes. The fusion of the CEP164 and APOC3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEP164-APOC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-RERE | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-REOR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-REGO | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-REGR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-REAQ | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-ORRE | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-OROR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-ORGO | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GORE | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GOOR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GOGO | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GOGR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GRRE | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GROR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GRGO | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GRGR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-AQRE | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-AQOR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-AQGO | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-AQGR | 20 (40 μL) | 200 μL |
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| CEP164-APOC3-20-AQAQ | 20 (40 μL) | 200 μL |
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APOC3 Gene Summary
This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]
Gene Name: Apolipoprotein C3
Chromosome: CHR11: 116700623 -116703787
Locus: 11q23.3
CEP164 Gene Summary
This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Centrosomal Protein 164
Chromosome: CHR11: 117198570 -117283982
Locus: 11q23.3
Gene Diseases
The CEP164 APOC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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